Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNSFMQQSRLKVILNMRHELREIFIKGCDDKIEKKGD----------NVGLS---FYAFFKNKNDNPELLMEAAHWWIMEHKLDHFEKAVKIKQLVLSEH 3CCY Chain:A ((9-57)) ----------------YENIRDTIIERAAAMFARQGYSETSIGDIARACECSKSRLYHYFDSKEA-----------------------------------

General information: TITO was launched using: RESULT: Template: 3CCY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 56 841 15.01 23.35 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : 15.01 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.658

(partial model without unconserved sides chains): PDB file : Tito_3CCY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3CCY-query.scw PDB file : Tito_Scwrl_3CCY.pdb: