Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFLAEFNQAPPDQLKTLLNNC-VHIPVWAEKIISERPYSSTSVLLGYAEQLSHTWSWQEIQAALATHPKIGERQAKKQLNAKEQNFSAQEQAGISL---DEQTQQALLQGNIEYEQKFGFIFLIKAAGLSSDEILKKLHQRLQNNLAIEKVIVHEQLAAIALLRLSQEVQA 2O73 Chain:B ((2-165)) -DINVVNALAYEDFVKLFGNVVEKCPLISAAIWSYRPFKDLADIEARISEFIHSLPDSGKEGILRCHPDLAGRDLQSGT---LTPESQEEQSQAGMTTLDSAEIVHMYRLNSEYKERFGFPFVICARLNNKADIVRQLSERLKNRRTAELECAIEEVKKICSLRLHSI---

General information: TITO was launched using: RESULT: Template: 2O73.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 649 4542 7.00 28.39 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain B : 0.70 3D Compatibility (PKB) : 7.00 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.580

(partial model without unconserved sides chains): PDB file : Tito_2O73.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2O73-query.scw PDB file : Tito_Scwrl_2O73.pdb: