Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -----------------DVEPPGASVKPTEAARRRVFKIDGEEFTPLETDCL--------IRIFKNKKTVHALFVPPGTELDWRLDHNHYAVGIKHNCDIIIGWKPSSWRIEGD------KVSSLADGFSVVT-TKSTD---------------------------- 1ZXU Chain:A ((24-212)) GGVVVDPKYCAPYPIDMAIVRKDGNFVITDVNGNLLFKVKEPVFGLHDKRVLLDGSGTPVVTLREDRWQVFRGGSTDQRDLLYTVKRTKLDVFLGHNKD-----KRCDFRVKGSWLERSCVVYAGESDAIVAQMHRKGKDNFSVTVYPNVDYAFIASLVVILDDVNR

General information: TITO was launched using: RESULT: Template: 1ZXU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 357 21560 60.39 211.37 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.57 3D Compatibility (PKB) : 60.39 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.57 QMean score : 0.120

(partial model without unconserved sides chains): PDB file : Tito_1ZXU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1ZXU-query.scw PDB file : Tito_Scwrl_1ZXU.pdb: