Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQMEMQLMAFELVDLDRQGTRMKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSKNPLL--SSAEIIVSSAVTRALETASYVVCATG---LPLRVEPLLHEWQVY-KTGIE--NFETA-----RRLFLENKG-----------EL----------LPNSPIQYETATEMKSRFLECMSKYRE-----HQTVVVVAHRMLMRQFVPN-----------EKIDFCQVIECELEI 1XQ9 Chain:A ((9-227)) ------------------MTTYTLVLLRHGESTWNKEN--KFTGW--TDVPLSEKGEEEAIAAGKYLKEKNFKFDVVYTSVLKRAICTAWNVLKTADLLHVPVVKTWRLNERHYGSLQGLNKSETAKKYGEEQVKIWRRSYDIPPPKLDKEDNRWPGHNVVYKNVPKDALPFTECLKDTVERVLPFWFDHIAPDILANKKVMVAAHGNSLRGLVKHLDNLSEADVLELNIPTGVPLVYELD-

General information: TITO was launched using: RESULT: Template: 1XQ9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 697 62 0.09 0.37 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : 0.09 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.358

(partial model without unconserved sides chains): PDB file : Tito_1XQ9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1XQ9-query.scw PDB file : Tito_Scwrl_1XQ9.pdb: