Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFV---WYNLFLKKEREVISMRKWTKGFLIFG-----------VVTTVI-GFILLFV--------GIQSDGIKSLLSMSKEPVYDSRTEKLTFGKE-VENLEITLHQHTLTI---TDSFDDQIH-IS-YHPSLS--------------AHHDLITNQND-RT-L-SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTIINASLENATLNTNSYILRIEGSRIKNSK---LTTPNIVNIFDT-VLTD-SQLESTENHFHAENIQVHGKVELTAKDYLR-IILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYKTEKTDVKDQLIARSDDNIDLISTPSRR 4YD8 Chain:A ((3-369)) LFKARDWWSTILGDKEE------FDQGCLCLANVDNSGNGQDKIIVGSFMGYLRIFSPHPAKTGDGAQAED-LLLEVDLRDPVLQVEVGKFVSGTEML--HLAVLHSRKLCVYSVSGTLGNQCQMKLMYEHNLQRTACNMTYGSFGGVKGRDLICIQS-MDGMLMVFEQESYAFGRFLP---GFLLPGPLAYSSR-TDSFLTVSSCQQVESYKYQVLAFATDA-DKLVVDWTLNIGEQALDICIVSFSASSVFVLGERNFFCLKDNGQIRFMKKLDWSPSCFLPYCSVSEGTINTLIGNHNNMLHIYQDVTLKWATQLPHIPVAVRVGCLHDLKGVIVTLSDDGHLQCSYL--------GTDPSLFQAP---

General information: TITO was launched using: RESULT: Template: 4YD8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2 117 58.50 0.40 target 2D structure prediction score : 0.43 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : 58.50 2D Compatibility (Sec. Struct. Predict.) : 0.43 1D Compatibility (Hydrophobicity) : 0.67 QMean score : ?

(partial model without unconserved sides chains): PDB file : Tito_4YD8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4YD8-query.scw PDB file : Tito_Scwrl_4YD8.pdb: