Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIGIDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLHYR-FHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDTDVKTAILTVPSVKSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED 1XCB Chain:C ((3-198)) -------VPEAAISRLITYLRILEELEAQGVHRTSSEQLGELAQVTAFQVRKDLSYFGSYGTRGVGYTVPVLKRELRHILGLNRKWGLCIVGMGRLGSALADYPGFGESFELRGF--FDVDPE-KVGRPVRGGV-IEHVDLLPQRVPGR-IEIALLTVPREAAQKAADLLVAAGIKGILNFAPVVLEVPKEVAVENVDFLAGLTRLSF------

General information: TITO was launched using: RESULT: Template: 1XCB.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 833 -58404 -70.11 -299.51 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain C : 0.79 3D Compatibility (PKB) : -70.11 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.671

(partial model without unconserved sides chains): PDB file : Tito_1XCB.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1XCB-query.scw PDB file : Tito_Scwrl_1XCB.pdb: