Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKFAGTLSGVVAETK--AHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDSSMSAQEIKDFAGL 3TCO Chain:C ((4-105)) --------DVTLVLTEENFDEVIRNNKLVLVDCWAEWCAPCHLYEPIYKKVAEKYKGKAVFGRLNVDE------NQKIADKYSVLNIPTTLIFVNGQLVDSLVGAVDEDTLESTVN-

General information: TITO was launched using: RESULT: Template: 3TCO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 434 -22543 -51.94 -225.43 target 2D structure prediction score : 0.76 Monomeric hydrophicity matching model chain C : 0.67 3D Compatibility (PKB) : -51.94 2D Compatibility (Sec. Struct. Predict.) : 0.76 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.712

(partial model without unconserved sides chains): PDB file : Tito_3TCO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3TCO-query.scw PDB file : Tito_Scwrl_3TCO.pdb: