Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVPLKGA-RDGHDFIETAFENGAAVTLSEKEV-SNHPYILVDDVLTAFQSLASYYLEK-TTVDVFAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMGQDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAPADPIVEDYLPIDK------KVVRFGQGAELEITDLVERKDSLTFKANF--LEQALDLPVTGKYNATNAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKLILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDV-LDIVIFYGEDIAQLAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKES----LGAHDQILLKGSNSMNLAKLVESLENEDK 4QDI Chain:A ((18-471)) EPWTAQQLQQATQGYWHKDQIPQTEIKRILTDSRHAESGDAFLALKGERFDAHNFVAQVVANGCQVAIVERPIDAEIAQLVVADTRLALGQLGAYRREQNAQLKVIALTGSSGKTTTKEMLGSILSRLAPTLITRGNLNNDLGVPMMLLELRKEHQYAVMELGANHQGEIDYTSKIVQPHVAGILNIGTAHLGEFGGRDGICRAKSEIYRHILPQGVAIVPQQDD---FTAEIREAAKSHQIMSFGEGGDVFATEIELLPQSANFQLHTPQGSSFVRLPFAGEHNVQNATAAVAFALALGVSLEDIVKGLEQAQGAKGRLNFIQK-APHLFIDDTYNANPTSMRAAAQVLLQQ----NGIKVMVMGDIGELGDSSWQEHHDLGRDL-AELPLDHIVAVGQFASAALEGAGLHS--TKLKAFQ--T-Q---AEALPFLINLIQTHQPQSMSFLFKGSRFTHMETLMADLMEK--

General information: TITO was launched using: RESULT: Template: 4QDI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2518 -4559 -1.81 -10.41 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : -1.81 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.502

(partial model without unconserved sides chains): PDB file : Tito_4QDI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4QDI-query.scw PDB file : Tito_Scwrl_4QDI.pdb: