Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -MFQGYSKDRREETCSYCGAIYI-----------VDIPGLPGH-----------EEREEYFCP----ECSHVNFARASNSPRVSLVKARTDG-----KNDKSPSFQALIDSYKDE 1FWQ Chain:A ((9-123)) ELVSAEGRNRKAVLCQRCGSRVLQPGTALFSRRQLFLPSMRKKPALSDGSNPDGDLLQEHWLVEDMFIFENVGFTKDVGNIKFLVCADCEIGPIGWHCLDDKNSFYVALERVSHE

General information: TITO was launched using: RESULT: Template: 1FWQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 236 14392 60.98 173.40 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : 60.98 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.359

(partial model without unconserved sides chains): PDB file : Tito_1FWQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1FWQ-query.scw PDB file : Tito_Scwrl_1FWQ.pdb: