Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ----MNMALKVSIASKSAHLTPEQIEEFGRRVEQIRQDVMQSLGEQDAKYIYKVRNFVRYTEIASRGMLMFGGWIPPVW---LLGTGLLGISKIVENMELGHNVMHGQFDWLNEPSLNGN---TYDWDTIASGDDWRETHNYVHHTYTNIVGKDHDIGYG---ILR--VSDQQKWEPRHLFNIPL--------ALQLMFFFEWYVGVQNLH--LEDALVYKTKSWKQVWEDAAKVRKKATRQVLKDYVFFPVISGPMFLPVFAG----------------NVVANIIRNLWSSAVIFNGHFT---------EDAETFEPDNTDTETKAEWYLRQIRGSSNFSGTEWLHFMSGNLSHQ----------------------IEHHLFPDMPANRYKEVAPKIKALCAEYGINYNEANFMRQFWSVWVRLAKCSLP---------------NHTTAKVMQTLEKLKAKFKFA------------------------------------------- 3WMT Chain:A ((18-522)) SFQAECESFKAKINVTNANVHSVTYVPAGVNISM--ADNPSICGGDPITSTFAFCRIALNVTTSSKSQIFMEAWLPSNYSGRFLSTGNGGLGGCVKYDDMAYAAGYGFATVGTNNGHFGNNGVSFYQNTEVVEDFAYRALHTGVVVGKELTKNFYPQGYNKSYYLGCSTGGRQGWKSVQTFPDDFDGVVAGAPAFNFINLTSWGARFLTLTGDSSAETFVTETQWTAVHNEIIRQCDSLDG--AKDGI---IEDPDLCQPIIEALLCNATQSSTSGTCLTGAQVKTVNGVFSATYGLNGSFLYPRMQPGSELAAYSSYYSGTPFAYAEDWYRYVVFNNTNWDVATWTVQDAAIANAQDPYQISTWNGDLSPFQKKGGKVLHYHGMEDAIIS-SESSKVYYKHVADTMNLSPSELDSFYRFFPI-SGMAHCANADGPSAIGQGTGTFAGNNPQDNVLLAMVQWVEEGVAPDFVRGAKLNGSTVEYRRKHCKYPKRNRYVGPGSYTDENAWECV

General information: TITO was launched using: RESULT: Template: 3WMT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2028 -8782 -4.33 -23.54 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -4.33 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.215

(partial model without unconserved sides chains): PDB file : Tito_3WMT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3WMT-query.scw PDB file : Tito_Scwrl_3WMT.pdb: