Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQQLMIMVTEVGKLEHTCNLLAEVNKGGKVIKVFD-YNGNELSMNMD-GIVTFN------RKRWELPVKVDLK----------------------------------------------- 3ZX7 Chain:A ((5-300)) AEGYEQIEVDVVAVWKEGYVYENRGSTSVDQKITITKGMKNVNSETRTVTATHSIGSTISTGDAFEIGSVEVSYSHSHEESQVSMTETEVYESKVIEHTITIPPTSKFTRWQLNADVGGADIEYMYLIDEVTPIGGTQSIPQVITSRAKIIVGRQIILGKTEIRIKHAERKEYMTVVSRKSWPAATLGHSKLFKFVLYEDWGGFRIKTLNTMYSGYEYAYSSDQGGIYFDQGTDNPKQRWAINKSLPLRHGDVVTFMNKYFTRSGLCYDDGPATNVYCLDKREDKWILEVVGLVPR

General information: TITO was launched using: RESULT: Template: 3ZX7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 77 2142 27.81 32.95 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.55 3D Compatibility (PKB) : 27.81 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.55 QMean score : 0.243

(partial model without unconserved sides chains): PDB file : Tito_3ZX7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3ZX7-query.scw PDB file : Tito_Scwrl_3ZX7.pdb: