Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFKNRFFNTMQIQNQVQLKPFNTLSLDVTASHYTKVKSIEDIEEALAFAK----EHELNVLVLSGGSNMLLPQ-QINALVIHLDIQGIDVLSEDQDFIRVKVGAGQVWHDFVLYTTKQNWFGLQNLALIPGLVGASPVQNIGAYGVEVGEFIESVQVYDRLLKQTGSISAADCHFSYRHSIFKDEP-ARYIITHVTFKLLKQ-ANLKLNYGDLK-Q---AVGDNLTAENLQNQVIHIRQSKLP--DP--KEYPNVGSFFKNPIVNTQEFERLIAQF-----STIPHYPQANGNVKIAAGWLIDQAGW-KGKQLGV---VGMFHKQALVLVNYANASLADVKKTYQAVQHDVEQRFQIMLEPEPVLYNNLGLIENHTE 5JZX Chain:C ((46-403)) ------FAGAHIAEAVPLAPLTTLRVGPIARRVITCTSAEQVVAALRHLDSAAKTGADRPLVFAGGSNLVIAENLTDLTVVRLANSGITID-----GNLVRAEAGAVFDDVVVRAIEQGLGGLECLSGIPGSAGATPVQNVGAYGAEVSDTITRVRLLDRCTGEVRWVSARDLRFGYRTSVLK---AVPTVVLEVEFALDPSGRSAPLRYGELIAALNATSGERADPQAVREAVLALRARKGMVLDPTDHDTWSVGSFFTNPVVTQDVYERLAGDAATRKDGPVPHYPAPD-GVKLAAGWLVERAGFGKGYPDAGAAPCRLSTKHALALTNRGGATAEDVVTLARAVRDGVHDVFGITLKPEPVLIGC---------

General information: TITO was launched using: RESULT: Template: 5JZX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1836 -30633 -16.68 -93.11 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain C : 0.77 3D Compatibility (PKB) : -16.68 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.427

(partial model without unconserved sides chains): PDB file : Tito_5JZX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5JZX-query.scw PDB file : Tito_Scwrl_5JZX.pdb: