Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -----------MEQIRPFPPTDFIDQADDEEATRLTPAPDLMD-----------------WVVKNYLTVDGELYNPDHDHI--------AELIHENEGFL--AFAWASQACTVKKQMVSGQCEKVMFNVG-GWRKARQEQQMRDWFGYVPVYLITIDASYCEQATDRDFCALIEHELYHIGVERDEDGE---------------PLYSEMTGLPKHYLAGHDVEE-----FVGVVKRWGADENVKRLIEVAKQAPFVSDVNISKCCGTCLIN 2Q7E Chain:A ((25-291)) PALTKSQTDRLEVLLNPKDEKPFRELESELLSRRKKDLQQIYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDNLSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPDPIKIFEIGPCYRKESDGKEHLEEFTMLNFCQMG------SGCTRENLESIITDFLNHLGIDFKIVGDSCMVYGDTLDVMHGDLELSSAVVGPIPLDREWGIDKPWIGAGFGLERLLKVKHDFKNIKRAARSESYYNGISTNL--------

General information: TITO was launched using: RESULT: Template: 2Q7E.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 598 1030 1.72 5.18 target 2D structure prediction score : 0.40 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : 1.72 2D Compatibility (Sec. Struct. Predict.) : 0.40 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.192

(partial model without unconserved sides chains): PDB file : Tito_2Q7E.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Q7E-query.scw PDB file : Tito_Scwrl_2Q7E.pdb: