Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSSLIQPELFFSALSPAEQRIQQALEDIRQGKPVLVMDDFDRENEADLIVAAETLTVETMVRMIHDGSGIVCLCLTEELADHLELPPMVSQNSSQFHTAFTVTIEAAQGVTTGVSAKDRVTTIKTAIKDGAVASDLNRPGHVFPLRARNGGVLTRRGHTEGTIDLARLAGLKPAGVLCELTNPDGTMASGIQVLAYAQTHHLTVITIEELVQYRQQHGI 4P6C Chain:B ((36-232)) -------------------RVENALQALREGRGVLLLDDEDRENEGDIIYAVESLTTAQMALMIRECSGIVCLCLTEAQADRLALPPMVVNNNSANQTAFTVSIEAKHGVTTGVSAQDRVTTIKTAANPQAKPEDLARPGHVFPLRARAGGVLARRGHTEGTVDLMQMAGLQPAGVLCELTNPDGSMAKTPEIIEFGKLHNMPVLTIEDMVQYRIQ---

General information: TITO was launched using: RESULT: Template: 4P6C.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1092 -127134 -116.42 -645.35 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain B : 0.86 3D Compatibility (PKB) : -116.42 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.86 QMean score : 0.580

(partial model without unconserved sides chains): PDB file : Tito_4P6C.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4P6C-query.scw PDB file : Tito_Scwrl_4P6C.pdb: