Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MISMKVVFHIDEL--E--KWSETGKNVKNLIKASPETTI-VVSVNGIAITGYLDSA------N-----AEFLDL-QGVVFHACANAMRANHIS-----------ESSLPEQVIVVPAGVLDLVELQSQGYAYIKP 2D1P Chain:G ((12-139)) --SMRFAIVVTGPAYGTQQASSAFQFAQALIAD--GHELSSVFFYREGVYNANQLTSPASDEFDLVRAWQQLNAQHGVALNICVAAALRRGVVDETEAGRLGLASSNLQQGFTL--SGLGALAEASLTCDRVVQ-

General information: TITO was launched using: RESULT: Template: 2D1P.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain G - contact count / total energy / energy per contact / energy per residue : 374 -23417 -62.61 -234.17 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain G : 0.64 3D Compatibility (PKB) : -62.61 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.579

(partial model without unconserved sides chains): PDB file : Tito_2D1P.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2D1P-query.scw PDB file : Tito_Scwrl_2D1P.pdb: