Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLKEKMFNRGILVASHGN-FASGALMTAEMFVGETTNDRVRTLGLMPGENIVEFEHYFKNQVNELLD--SNQEVIVLTDLIGGSPNNVALSRFLN-LDSVDIVTGFNIPLLVELISSYDSKINLEE----IVHNAQNSLFNVKQQLNVEEEEDLCL 3GDW Chain:A ((2-135)) -----NANVGVFVLMHGDSTASSMLKTAQELLGT--S-IGTAMNMPLTMEVQTMYEQLRNQVITQ-KESLNNGILLLTDM--GSLNSFGNMLFEETGIRTKAITMTSTMIVLEAIRMASVGRSLEDIYQNIQLSFESVVREQFRS-----------

General information: TITO was launched using: RESULT: Template: 3GDW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 605 -31788 -52.54 -252.28 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -52.54 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.449

(partial model without unconserved sides chains): PDB file : Tito_3GDW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3GDW-query.scw PDB file : Tito_Scwrl_3GDW.pdb: