Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MCCFVVYGG--------VLNMSDKKTS---------------LVICFTPLQMLIAEKIVAQQPSV----------DLIVIALNNNDKYKYYYNIFQHPNIAKQYY--LFDNNKSRFFKFINIIKFNENFKLE------------KFYENIYISSIDNKYTHNILS-------KVNFNNLYTYDDGTANIVKNSIYFKQTFESKLKDIVLKLIGIRFNLNKIKKLSRK--HYTIYKG------IQNIVEQTEYV-----------SIIEKKEE--DRNIFID----QEIKIFLGQPLKDIDKNFDTLALKKLLVMEEVNYHFKHP-----------RETDEAFFEEIKTSYIFEDF---------------------FAKELS-------KYRKVII-------------------YTLSSTAALNIISLDNVEIRLIKNNT-VEIKYPDLVQLFIKSGATVIDMDSIK-------------------------- 4GA6 Chain:A ((1-493)) MKAKIRILDMFSGRYTVLINEEDAKEAKLHPDDLVKIEAGKKAVYGSVALSNLVGKGEVGISRDVLDLHNFSEGETVSVIPAGTPESVRYIKKKMHGEKLRKVEIEAIVRDIVDRKLRDIEISSFVTALEINGLDMDEIAALTIAMAETGDMLDIDRKPIMDVHSIGGVPGNKTNILVVPIVAAAGLTIPKTSSRAITSAAG-TADVVEVFADVSFSLDEIKRIVEKVGACLVWGGALNLAPADDITIKAERALSIDPTGLMLASIMSKKYAMGSQYVLIDIPTGKGVKVETVEEARSLARDFIELGKRLGQYVEVAITYGGQPIGHTVGPALEAREALSALMTGKGPGSLIEKATGLAGILLEMGGVAPAGTGKKMAKEILESGKAWEKMKEIIEAQGGDPNIKPEEIPIGDKTYTFTAATSGYVTAIDNRAITAIARAAGAPEDKGAGIELYVKVGEKVKEGDPLFTIHAEHEARLDQAIVLARRTEPIRIE

General information: TITO was launched using: RESULT: Template: 4GA6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1828 29121 15.93 88.51 target 2D structure prediction score : 0.39 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : 15.93 2D Compatibility (Sec. Struct. Predict.) : 0.39 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.056

(partial model without unconserved sides chains): PDB file : Tito_4GA6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4GA6-query.scw PDB file : Tito_Scwrl_4GA6.pdb: