Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSIKKRGLAKGRGLDALLGSIQKEKLQLEAQALDHGQLKQIDVKLLKRGEYQPRRFIHEHDLQELASSIEKHGVMQPIVIRPVDDEAHPYEIIAGERRWRAAQIAGLTEIPAIVRDLNDQVAIALALIENIQRQDLNPIDQALALQRFHDEFGLSHQEIADTVGKARTTVSNLLRLLSLADDIKEFMQQGQLDMGHARAILTLKGKEQLEVAKIVIEKGLSVRQTEQLVRDWNEPKQEKEKAPVAPDIEQLTQKLSERFGANVKIDHNQKGKGKLVIHYHSLDELDGILNICLPD 1VZ0 Chain:B ((23-214)) -------------------------------------VVRLPLASIRPNPRQPRKRFAEESLKELADSIREKGLLQPLLVRPQ---GDGYELVAGERRYRAALMAGLQEVPAVVKDLTDREALELALVENLQREDLSPVEEARGYQALLEM-GLTQEEVARRVGKARSTVANALRLLQLPPEALEALERGEITAGHARALLMLEPEDRLWGLKEILEKGLSVRQAEALRERLA--------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1VZ0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 634 -88384 -139.41 -460.33 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain B : 0.77 3D Compatibility (PKB) : -139.41 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.673

(partial model without unconserved sides chains): PDB file : Tito_1VZ0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1VZ0-query.scw PDB file : Tito_Scwrl_1VZ0.pdb: