Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNISYELEKKIVNLNALYNEEEAELSLRLSQNIRKNQQDGYVYSLISRGFE-------IKGLKLWL--VDKNIDQLKQWFYVSSVLRAESCKYSSGYTLSTPDEFIFPLLSDNTEIINKFAYLDTVNLLWGEFEPSYQ-------EAKFKPSKDDPRF-RTHALQAVLRN---DWEDY---------KKIKEVANQKINKLREVVQFEF-----GIYDAIYEKDKDKIIEIVQTLLNPRVHKTYNKDFGEEFNGEIWSHHPVMFTKLAWMNGLEIEIDNPLVPMELMPIKPLEHYDYHYD-----FLDPNWKPKSLFEKLFGKKRNK 1DKI Chain:A ((37-371)) LDKVN------------LGGELSGSNMYVYNGFVIVSGDKRSPEILGYSTSGSFDVNGKENIASFMESYVEQIKENKKLPVVKSLLDSKGIHYNQGNPYNLLTPVIEKVKPGEQSFVGQHAATGSVATATAQIMKYHNYPNKGLKDYTYTLSSNNPYFNHPKNLFAAISTRQYNWNNILPTYSGRESNVQKMAISELMADVGISVDMDYGPSSGSAGSSRVQRALKENFGYNQSVHQINRGDFSKQDWEAQIDKELSQNQPVYYQGVGKVGGHAFVIDGA-------DGRNFYHVNWGWGGVSDGFFRLDALYQSAVVGIKP-----

General information: TITO was launched using: RESULT: Template: 1DKI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1265 64224 50.77 243.27 target 2D structure prediction score : 0.42 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 50.77 2D Compatibility (Sec. Struct. Predict.) : 0.42 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.138

(partial model without unconserved sides chains): PDB file : Tito_1DKI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1DKI-query.scw PDB file : Tito_Scwrl_1DKI.pdb: