Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --------------------------------------------------------------------------------------MLHLHVHPENPQ-QRLIEQAVERIRAGDVVVYPTDAAYAIGCQIGNKNAMERIAQIRGLGPKHQYAIMCCDLSDIATYAKVDNATYRLLKANTPAITTFILPATSEVPRRLMHPKKKTIGLRIPSNPICQALLKELGGPLLTSTLILPGQEDPLDDPYDIENQLAKRIDVFI--DGGFGTLTTTSIVDLSGEHPEIIRHGVGDVSAFE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3TTC Chain:A ((12-657)) QIVPDAATCPACLAEMNTPGERRYRYPFINCTHCGPRFTIIRAMPYDRPFTVMAAFPLCPACDKEYRDPLDRRFHAQPVACPECGPYLEWVSHGEHAEQEAALQAAIAQLKMGNIVAIKGIGGFHLACDARNSNAVATLRARKHRPAKP-LAVMLPVAD------GLPDAARQLLTTPAAPIVLVDKKYVPELCDDIA-PGLNEVGVMLPANPLQHLLLQELQCPLVMTSGNLSG-KPPAISNEQALEDLQGIADGFLIHNRDIVQRMDDSVVR---ESGEMLRRSRGYVPDALALPPGFKNVPPVLCLGADLKNTFCLVRGEQVVLSQHLGDLSDDGIQTQWREALRLMQNIYNFTPQYVVHDAHPGYVSCQWASEMNLPTQTVLHHHAHAAACLAEHQWPLDGGDVIALTLDGIGMGENGALWGGECLRVNYRECEHLGGLPAVALPGGDLAAKQPWRNLLAQCLRFVPEWQNYPETASVAAANWSVLARAIERGINAPLASSCGRLFDAVAAALGCAPATLSYEGEAACALEALAASCDGVTHPVTMPRVDNQLDLATFWQQWLNWQAPVNQRAWAFHDALAQGFAALMREQATMRGITTLVFSGGVIHNRLLRARLAHYLADFTLLFPQSLPAGDGGLSLGQGVIAAARWLAGE

General information: TITO was launched using: RESULT: Template: 3TTC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 722 9284 12.86 48.10 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.57 3D Compatibility (PKB) : 12.86 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.57 QMean score : 0.537

(partial model without unconserved sides chains): PDB file : Tito_3TTC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3TTC-query.scw PDB file : Tito_Scwrl_3TTC.pdb: