Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVSTPCKLRGDDFMAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQEAQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILPAFGK--LKLSNISVPYCQKVVDEWHSK---YESYDYMRKQTAQILRYGVAMQYIDNNPMEKT----LLPRKK--E---YEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKDIDTFN-KELHVNKTLAVDEFGKVIIQSPKT--RASRRVISLDTETLSILNNWKLQQKEEYLKLGYNTSSKEQHVFTTVKN---------TLYIPNTVNDWLRY-------ILKKYNLP---RITPHGFRHTHASLLLEAGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ 1CRX Chain:A ((17-321)) -----------------------------------------------------------------------------------------------AFSEHTWKMLLSVCRSWAA-WCKLNNRKWFPAEPEDVRDYLLYLQARGLAVKTIQQHLGQLNMLHRRSGLPRPSDSNAVSLVMRRIRKENVDAGERAKQALAFERTDFDQVRSLMENSDRCQDIRNLAFLGIAYNTLLRIAEIARIRVKDISRTDGGRMLIHIG------------RTKTLVSTAGVEKALSLGVTKLVERWISVSGVA--------DDPNNYLFCRVRKNGVAAPSATSQLSTRALEGIFEATHRLIYGAKDD-SGQRYLAWSGHSARVGAARDMARAGVSIPEIMQAGGWTNVNIV-MNYIRNLDSETGAMVRLLE------

General information: TITO was launched using: RESULT: Template: 1CRX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1086 34791 32.04 129.33 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : 32.04 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.346

(partial model without unconserved sides chains): PDB file : Tito_1CRX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1CRX-query.scw PDB file : Tito_Scwrl_1CRX.pdb: