Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence CIMGFISKERERALLKDQQPGTFLLRFSESSREGAITFTWVERSQNGGEPDFHAVEPYTKKELSAVTFPDIIRNYKVMAAEN 1YVL Chain:A ((577-657)) CIMGFISKERERALLKDQQPGTFLLRFSESSREGAITFTWVERSQ---EPDFHAVEPYTKKELSAVTFPDIIRNYKVMAAE-

General information: TITO was launched using: RESULT: Template: 1YVL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 252 -34310 -136.15 -439.87 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.99 3D Compatibility (PKB) : -136.15 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.99 QMean score : 0.781

(partial model without unconserved sides chains): PDB file : Tito_1YVL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1YVL-query.scw PDB file : Tito_Scwrl_1YVL.pdb: