Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVM-----GALGGFGGMFDLSKTGVKEPVLISGTDGVGTKLMLAIKY-------DKHDTIGQDCVAMCVNDIIAAGAEPLYFLDYV-ATGK--NEPAKLEQVVAGVAEG---CVQAGAAL--IGGETAEMPGMYGEDDYDLAGFAVGVAEKSQIIDGSKVVEGDVLLGLVSSG-----------IHSNGYSLVRRVFADY----TG--EEVL--P-------------EL--EGKKLKEVLLEPTRIYVKAVLPLIKE--ELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVLPIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELL---DEAVYEIGRIVKKEN-ESVIIK 3KIZ Chain:A ((28-383)) ---------------------------DKGIY-PRAFCKIIPDILGGDP-----------EYCNIMHADGAGTKSSLAYVYWKETGDISVWKGIAQDAVIMNIDDLICVGAVDNILLSSTIGRNKNLIPGEVLAAIINGTEEVLQMLRDNGIGIYSTGGETADVGDLVRT--IIVDSTVTCRMKRQDVISNENIKAGNVIVGFASYGQTSYETEYNGGMGSNGLTSARHDVFNNVLASKYPESFDPKVPENLVYSGEMNLTDPYLNVPLDAGKLVLSPTRTYAPLMKEIIHQYKGKLDGVVHCSGGGQTKVLHF--TDATTHIIKDNLFDVPPLFQLIQGQSNTPWEEMYKVFNMGHRLEIYTDAAHAEGMIAIAKKFNIEAKIIGRVEAPVAGKRLTI-

General information: TITO was launched using: RESULT: Template: 3KIZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1567 8431 5.38 28.48 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 5.38 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.470

(partial model without unconserved sides chains): PDB file : Tito_3KIZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3KIZ-query.scw PDB file : Tito_Scwrl_3KIZ.pdb: