Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIAVAGTGYVGLSIAVLLSQ-QHQVMAVDIIPEKVELINQRKSPIQDDYIEKYLAK--KDLNLVATLDAKEAYQDADFVVIAAPTNYDPKKNFFDTSAVESVIETALKY-NPDAIMVIKSTVPVGYTESARKKF------QTENILFSPEFLRESKALYDNLYPSRIILGTDKNNERLVSAAETFARLLQEGALKENIDTLYMGFTEAEAVKLFANTYLALRVSYFNELDTYSEMKGLDTQAIIDGVGLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANY--EDIPEELIGAIVRSNSTRKDFIADQVLKMVDYYDYSAHNIFDERVEKDIIIGIYRLTMKSNSDNFRQSSIQGIMKRIKAKGVRVVIYEPTLESGSTF--FGSSVINDLEEFKRLSNAIVANRYDNSLEDVK-----E------KVYTRDIFERD 4A7P Chain:A ((9-426)) VRIAMIGTGYVGLVSGACFSDFGHEVVCVDKDARKIELLHQNVMPIYEPGLDALVASNVKAGRLSFTTDLAEGVKDADAVFIAVGTPSRRGDGHADLSYVFAAAREIAENLTKPSVIVTKSTVPVGTGDEVERIIAEVAPNSGAKVVSNPEFLREGAAIEDFKRPDRVVVGTEDE-----FARQVMREIYRPLS-----PVLFTGRRTSELIKYAANAFLAVKITFINEIADLCEQVGADVQEVSRGIGMDNRI---FLHAGPGYGGSCFPKDTLALMKTAADNETPLRIVEATVQVNDARKRAMGRKVIKAMGG------------DVRGKTVGILGLTFKPNTDDMRDAPSLSIIAALQDAGATVKAYDPEGVEQASKMLTDVEFVENPYAAADGADALVIVTEWDAFRALDLTRIKNSLKSPVLVDLRNIYP--

General information: TITO was launched using: RESULT: Template: 4A7P.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2064 34311 16.62 89.12 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : 16.62 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.501

(partial model without unconserved sides chains): PDB file : Tito_4A7P.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4A7P-query.scw PDB file : Tito_Scwrl_4A7P.pdb: