Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKLVFVCLGNICRSPMAEFVMKSM------TDNYEIQSRATSSWEHGNPIHKGTQGIFQQYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDL-RQMCPVD-CQDKIYSFSSES------VPDPWYTG--DFEETYRRVQEGCQAWLERLEKES 1XWW Chain:A ((6-155)) -KSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWVIDSGAVSDWNVGRSPDPRAVSCLRNHGI--HTAHKARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEK-----

General information: TITO was launched using: RESULT: Template: 1XWW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 655 12305 18.79 91.83 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : 18.79 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.502

(partial model without unconserved sides chains): PDB file : Tito_1XWW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1XWW-query.scw PDB file : Tito_Scwrl_1XWW.pdb: