Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MHLAQRLAAVVLTLGLSAGLVGCGFHLKGTNPTATPLVYKKLSL-ELPAKTDDLETQLKVYLTANGVQLSNDN-DAYVLRVLEYTPRRQLL----NGKLTEVLLRLTVTFQIEDRQGNKITEPRTLTAARSYQYDLATVNTENQQESYLQRIVIDDLAQQITRQISANRLPKAQP 2R76 Chain:A ((36-164)) ---------------------------------------NQLSLSSSDEY-KELTRLVRERLRLNNVKIVDAANDVPVLRLITDSLERSTLSLYPTGNVAEYELIYFVEFAVALP-GKEAQ-PFKIEIRRDYLDDPRTALAKSREMELLVKEMRIQAADRILQSMASTEVN----

General information: TITO was launched using: RESULT: Template: 2R76.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 466 26553 56.98 215.87 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : 56.98 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.479

(partial model without unconserved sides chains): PDB file : Tito_2R76.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2R76-query.scw PDB file : Tito_Scwrl_2R76.pdb: