Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVSYSASYLPRMQQNLTLLQHYHENKENCMSFSMTKLSAALLLTSSLVGCAAVVKTPYQAPAVQVPGSFQYDKAKAKTASVEQYSDHWWTLFGDAQLNQLVTNVLERNSDLAVAGITLKQARLQADLTANKQGLRTSSSVSTGHSFDLNS-G-DDSAKGLSMSAGVSYELDLFGKLARQTEASKWEALATEQDLQSTGQSLIATTAKLYWQLGYLNERYATAQQSLATSQKLYQLVQTQYKAGAVSGLDLTQAEQSVQSQKASLSQIEQQLVETRTAIAVLLHEPVQQLN-I-QEP-QRLPRTALPAIGAGLPADILSRRPDLQAAELRLRKALATKDATKASYYPSISLTSSLGSSSTSLTELL--RNP-ALTLGASLSLPFLQYNDIKKDIAISNLDYEKAIIQYRQTLYQAFADVENALSSRTELDKQVALQERNVELAEKTERLTEVRYRYGAVALKTLLDAQQTTRTARLSLVETKQSQYNAYVTLMQALGGSPVKELPQ 4K7R Chain:A ((1-440)) --------------------------------------------------CSLAPD-YQRPAMPVPQQFSL-----------YQNAGWRTFFVDNQVKTLISEALVNNRDLRMATLKVQEARAQYRL--TDADRYPQLNGEGSGSWSGNLKGNTATTREFSTGLNASFDLDFFGRLKNMSEAERQNYLATEEAQRAVHILLVSNVAQSYFNQQLAYAQLQIAEETLRNYQQSYAFVEKQLLTGSSNVLALEQARGVIESTRSDIAKRQGELAQANNALQLLLGSY-GKLPQAQTVNSDSL-Q--SVKLPAGLSSQILLQRPDIMEAEHALMAANANIGAARAAFFPSISLTSGISTASSDLSSLFNASSGMWN-FIPKIEIPIFNAGRNQANLDIAEIRQQQSVVNYEQKIQNAFKEVADALALRQSLNDQISAQQRYLASLQITLQRARALYQHGAVSYLEVLDAERSLFATRQTLLDLNYARQVNEISLYTALGGG-------

General information: TITO was launched using: RESULT: Template: 4K7R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1508 55172 36.59 131.05 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : 36.59 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.370

(partial model without unconserved sides chains): PDB file : Tito_4K7R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4K7R-query.scw PDB file : Tito_Scwrl_4K7R.pdb: