Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSSTQFDHVTVIKKSNVYFGGACISHTVQFEDGTKKTLGV-ILPTEQPLTFETHVPERM-EIISGECRVKIADSNESELFRAGQSFYVPGNSVFKIETDEVLDYVCHLEG 2OYZ Chain:A ((1-94)) ----------ASIKENSYFAGGVKSLGFNQ-HGQDVSVGVML---PGEYTFGTQAPE-RMTVVKGALVVKRVGEADWTTYSSGESFDVEGNSSFELQVKDATAYLCEYL-

General information: TITO was launched using: RESULT: Template: 2OYZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 387 -13045 -33.71 -141.79 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -33.71 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.522

(partial model without unconserved sides chains): PDB file : Tito_2OYZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2OYZ-query.scw PDB file : Tito_Scwrl_2OYZ.pdb: