Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKYCQFFSVLALGLSAASCAVTSGLQTYDIPSEGVYKTDLGTTVNVVKISQETLPAIQPAQIDYQRDYASLFKNQQTIYRLSPGDVLSIQLWAYPEIAPPVNNISNEQSVQAYGYPIDQTGYIQFPLVGRYKAAGKTLAQVNRELHSQLARFLKNPDVVVRVVSYEGQRFSVQGSVTKGGQFYLSDQPVSIYTALGMAGGVTTTGDNTYIQLIRNG-RTYNLNTIDLEKAGYSLHKLLVQPNDTIYVSTRENQKIYVMGESGKNQALPMRDQGMSLTDALGESLGINPLSGSASRIYVVRTNPNDRTTEIYHLNLMSIGDFGLANQFRLRSNDVVYVDATGLTRWQRIVNQIIPFSNALYNIDRLGQ 3P42 Chain:A ((126-204)) ---------------------------------------------------------------------------------------------------------------------------------------------------------------------RPVTITLLGAVSGAGQLPWL-AGRSVTDYLQDHPRL-AGADKNNVMVITPEGETVVAPVAL-W----NKRHVEPPPGSQLWLGFSA--------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3P42.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 345 -26963 -78.15 -345.67 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.52 3D Compatibility (PKB) : -78.15 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.52 QMean score : 0.424

(partial model without unconserved sides chains): PDB file : Tito_3P42.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3P42-query.scw PDB file : Tito_Scwrl_3P42.pdb: