Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTDLNKKREVNLSF-----EQDDGAVW-VFDGDSHQ---GTEISHLMMMHSD-------E-YNEDELRVICNHAAFEIDRLRAELEKSKAQAVPEAQQKLTDTYFWEGSDYVVD------CPFE-YDIELDKGEV---LELQKWQRTESTKVYFANIYKDEDNFEI--LQFASKAEAENAVAEN-LKFLEASESGAEG 3P06 Chain:A ((1-194)) NGVELSAVGVLLPVLMDSGRRISGGAFMAVKGDLSEHIKNPKNTRIAQTVAGGTIYGLSEMVNIDEAEKLPIKGAITV--LPVVQATATSILVPDNQPQLAFNS-WEAAACAADTLESQQTPFLMVTGAVESGNLSPNLLAVQKQLLVAKPAGIGLAANSDRALKVVTLEQLRQVVGDKPWRKPMVTF-SSGKNVAQA

General information: TITO was launched using: RESULT: Template: 3P06.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 913 50376 55.18 307.17 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : 55.18 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.076

(partial model without unconserved sides chains): PDB file : Tito_3P06.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3P06-query.scw PDB file : Tito_Scwrl_3P06.pdb: