Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTAKDEYFLETSSSKRIIVCLLDVFVSISTIRYLFFIARCENMFHNREVRKKLSNGGQKMKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTITYGFGHLVDMVAPGAYEE-RWA--KWSLENLPIFP-ETFRYEVP--MDKRAQFSIVKRELQSADTIIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYFPKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIKHFKKETYFEGEGLITTNKG-------QFSGKIVP----------------------KKAFKTQEELTKEIEKLGAHLGKQNGRILEVTKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITENEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTI---PTPA--RFAKLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGV----QQLKLKSIGKIPLQQGWQEILRIKSKK-------KEAQTLPPIVENEEAEV-ELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEAQEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANE-PLLTSAEMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKV-DF-SDEISGTRQIKAMEKKNDQLGRCPKCKKGIVML---YPKIATCLNP------E-CDFKLWPTVAKKKLTKTNLRDLLSKGKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENEVE 5D5H Chain:A ((19-705)) -----------------------------------------------------------GRRLVIVESPTKARKLASYLGS-----------------GYIVESSRGHIRDLPRAASDVPAKYKSQPWA--RLGVNVDADFEPLYIISPEKRSTVSELRGLLKDVDELYLATDGDREGEAIAWHLLETLK---PRIPVKRMVFHEITEPAIRAAAEHPRDLDI--DLVDAQETRRILDRLYGYEVSPVLWKKVA-----PKLSAGRVQSVATRIIVARERDRMAFRSAAYWDILAKLDASVSDPDAAPPTFSARLTAVAGRRVATGRDFDSLGTLRKGDEVIVLDEGSATALAAGL---DG-TQLTVASAEEKPYARRPYPPFMTSTLQQEASRKLRFSAERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYG---DEYVAPAPRQYTRKVKNA--QEAHEAIRPAGETFATPDAVRRELDGPNIDDFRLYELIWQRTVASQMADARGMTLSLRITGMSGHQEVVFSATGRTLTFPGFLKAYVETVDELVGGEADDAERRLPHLTPGQRLDIVELTPDGHATNPPARYTEASLVKALE-----------------ELGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDEIAAGNERRTNWLNNFYFGGDHGVPDSVARSGGLKKLVGINLEGI----DAREVNSIKLFDDTHGRPIYVRVGKNGPYLERLVAGDTGEPTPQRANLSDSITPDELTLQVAEELFA-------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 5D5H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 3316 144456 43.56 232.24 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : 43.56 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.386

(partial model without unconserved sides chains): PDB file : Tito_5D5H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5D5H-query.scw PDB file : Tito_Scwrl_5D5H.pdb: