Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRTRRLGQTLFSQPFLGEISMNLTIQEIAQAVG-SECSALTKITNVEFDSRKITEGSLFVPLAG-TRDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEVVAITGSNGKTTTKDLTASVLSEKY----KTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMGMDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVPADEPLLTPLTA-TLVQTVTTFGIG--NGDVHAEVTAKG-KAQTDFVVE----GETFTIPLPGSYNVTNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMGLVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHALKEELNQKYPQLPVFYLEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK 4CVK Chain:A ((2-451)) -------------------LEPLRLSQLTVALDARLIGEDAVFSAVSTDSRAIGPGELFIALSGPRFDGHDYLAEVAAKGAVAALVEREVA---APLPQLLVRDTRAALGRLGALNRRKFTGPLAAMTGSSGKTTVKEMLASILRTQAGDAESVLATRGNLNNDLGVPLTLLQLAPQHRSAVIELGASRIGEIAYTVELTRPHVAIITNA-------FGGPEKIVEAKGEILEGLAADGTAVLNLDDKAFDTWKARASGRPLLTFSLDRPQADFRAADLQRDARGCMGFRLQGVAGEAQVQLNLLGRHNVANALAAAAAAHALGVPLDGIVAGLQALQPVKGRAVAQLTASGLRVIDDSYNANPASMLAAIDILSGF--SGRTVLVLGDMG-----AEQAHREVGAYAAGK-VSALYAVGPLMAHAVQAFGA-----TGRHFA-DQASLIGALAT-EDPTTTILIKGSRSAAMDKVVAALC---

General information: TITO was launched using: RESULT: Template: 4CVK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2446 6718 2.75 15.88 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : 2.75 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.496

(partial model without unconserved sides chains): PDB file : Tito_4CVK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4CVK-query.scw PDB file : Tito_Scwrl_4CVK.pdb: