Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDRLQQFYIFTEVAKRQSFSEVANQLDLPRSTVTSAIQQLETHYGVRLFHRTTRKVSLTQDGQRILPECQNLLFDYEQLEQLIQTQKQHYRGTLKISMPSRIVHQVIIPELPDFYHRYPDIHLQLNSSD--D-LTDLIEKGIDCVVRVGEL--DNSSLIARFIGHLVMVNCASTQYLQDYGIPEQLNDLEQHKLINYAGAVG-EK--QGEFIYQGGTV-MMDSALSVNNTEAYIAAACAGLGIIQLPYYDVQDKIEQGILVEVLSAYIAPSLPLNILYPNRSYIPKRLEVFMNWVGEVLNRKCIVIF 3FXQ Chain:A ((1-296)) MLKLQTLQALICIEEVGSLRAAAQLLHLSQPALSAAIQQLEDELKAPLLVRTKRGVSLTSFGQAFMKHARLIVTESRRAQEEIGQLRGRWEGHITFAASPAIALAALPLALASFAREFPDVTVNVRDGMYPAVSPQLRDGTLDFALTAAHKHDIDTDLEAQPLYVSDVVIVGQRQHPMANA--TRLAELQECRWAFSSAPRGPGAIIRNAFARYG--LPEPKLGLVCESFLALPGVVAHSDLLTTMPRTLYERNAFKDQLCSIPLQDALPNPTIYVLRRHDLPVTPAAAGLIRWIQHHAL-------

General information: TITO was launched using: RESULT: Template: 3FXQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1269 -91333 -71.97 -318.23 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -71.97 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.416

(partial model without unconserved sides chains): PDB file : Tito_3FXQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3FXQ-query.scw PDB file : Tito_Scwrl_3FXQ.pdb: