Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---------MATRITNQKLSKSSR----AWMREHLDDPFVKKAQKEGYRARAAYKLLEIQEKYKLIKPGMTVVDLGAAPGSWSQIAGKLVGSKGLVIASDILPMDALPDVTFLQGDFREEAVFEKLLNILNGR--QVDIVISDMAPNTSGNRAVDQPRQIYLCELALDFAQKVLGPNGQFVVKVFQGAGFDEFRKQVVDSFDVLKTA------KPAASRARSKEVFLVGQGRKKALQ------------------------------------- 1L9K Chain:A ((16-276)) ETLGEKWKSRLNALGKSEFQIYKKSGIQEVDRTLAKEGIKRGETDHHAVSRGSAKLRWFVER-NLVTPEGKVVDLGCGRGGWSYYCGGLKNVREVKGLTKGGPGHEEPIPMSTYG--WNLVRLQSGVDVFFIPPERCDTLLCDI-----GESSPNPTVEAGRTLRVLNLVENWLSNNTQFCVKVLNP-----YMSSVIEKMEALQRKHGGALVRNPLSRNSTHEMYWVSNASGNIVSSVNMISRMLINRFTMRHKKATYEPDVDLGSGTRNIGI

General information: TITO was launched using: RESULT: Template: 1L9K.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 916 16321 17.82 80.40 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : 17.82 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.434

(partial model without unconserved sides chains): PDB file : Tito_1L9K.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1L9K-query.scw PDB file : Tito_Scwrl_1L9K.pdb: