Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIFIEYKIITLFISLKIKKGVFIMKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIKMYQIGDKP-D--NLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAFADN-Y-IVNAQKGAYADLTELYKKEGKDLYKALDP---AYIKGN-TVNGKIYAVPVAAN---VASSQNFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDV------VPFAIGKVFI-PSDNFD-YPV--ANGLP----------FVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTS----FDLQQDTWFVRE--ETVGPADYGNSLLSRVANKDIQIKPITNFI-KK--N-------QTTQVANFVISNNSKNKEKSMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLD-GYK--GN---TH-MGG--WNTGNNWILYIN-ENVTDQQIENS------KKELAE-AKE-SPALGFI-FNTDNVKSEISAIANTMQQFDTAIN--TGTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK 3OMB Chain:A ((33-535)) -----------------------------------------------------TT---TADGKPIVTVLVKKNANQEKMANMQWAKDLE----ADCDCKIEWQEVTREAWAQQKNATLASGDIADVNLNGYGAVEAYQYPGMFEDLSKDLDKL-PNV-KAFFKQKPDAKKMSTDSKGRIYAIADGRGKAYSGTGQHMLINKAWLDKLGLQV--PTTWDELENVLKAFKTQDPNGNGQADEIPMNIKKLEGSYFTWYSPMLLLNSTGIVTGFNKGVSEYGFY--A-KNGVVKSFLTSDEYKEVIKYYHKLISEGLIPAEWATKDDDAYNADQISDGKTAKTGVVFGWSPS---DNFGK--LKDQYIAMPVPSAPGVSPDQTVWDGSSSELSPAGLSISSHAANKDAALKLANLLYSE-KYSVQQFLGSFGKAITKTGEHEY--TVDNDKLSQLTGDNQYPGLSELLVGWIPD-EATIKGDTHADELIEVNKVYEEQRSHFDPVKDYIPDYVNMDNMDPSDATKLNTNNAEIFNTTMQKTATWMSKGGIDEEWDAYCKQLDSIG-LQESTKIWQKWYDTYTK---

General information: TITO was launched using: RESULT: Template: 3OMB.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2382 159682 67.04 367.93 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : 67.04 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.398

(partial model without unconserved sides chains): PDB file : Tito_3OMB.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3OMB-query.scw PDB file : Tito_Scwrl_3OMB.pdb: