Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTARRDLIFHNGAVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYTGKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQSGHI-CDAKTIMAVQYWELQKK 1V8Y Chain:A ((11-164)) ---------RTYLYRGRILNLALE----------GRYEIVEHKPAVAVIALR-EGRMLFVRQMRPAVGLAPLEIPAGLIEPGED--PLEAARRELAEQTGLSGDLTYLFSYFVSPGFTDEKTHVFLAENLKEVE----------IEVVWMRPEEALERHQRGEVEFSATGLVGVLYYH----

General information: TITO was launched using: RESULT: Template: 1V8Y.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 674 -79417 -117.83 -547.70 target 2D structure prediction score : 0.40 Monomeric hydrophicity matching model chain A : 0.81 3D Compatibility (PKB) : -117.83 2D Compatibility (Sec. Struct. Predict.) : 0.40 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.247

(partial model without unconserved sides chains): PDB file : Tito_1V8Y.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1V8Y-query.scw PDB file : Tito_Scwrl_1V8Y.pdb: