Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -------MTKKGSFMPASTSQYYTRT---------------AQILHWVM------------AIIFITAWVIGFYS-GNFLSYDVDGSFKGDVITLHKNIATTIIFLVVIRLFWRY----------THPAPQLPDTMSPTMKTLAHIGHLLLYVILVALPVTG-------------------CLFSWSAGHPAP--VLYLFEIPRLVQDNPEL-------LAIVKPLHIYISWFAGFLIVGHVLAALKHHFVDK------DNVLNSMTKQPK 5J9T Chain:C ((8-279)) MTWNEYDKFYTGSFQETTSYIKFSATVEDCCGTNYNMDERDETFLNEQVNKGSSDILTEDEFEILCSSFEHAIHERQPFLSMDPESIL--SFEELKPTLIKSDMADFNLRNQLNHEINSHKTHFITQFDPVSQMNTRPLIQLIEKFGSKIYDYWRERKIEVNGYEIFPQLKFERPGIDPYVCFRRREVRHPRKTRRIDILNSQRLRALHQELKNAKDLALLVAKRENVSLNWINDELKIFDQRVKIKNLKRSLNISGEDDDLINHKRKRP-

General information: TITO was launched using: RESULT: Template: 5J9T.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 529 -20629 -39.00 -109.15 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain C : 0.62 3D Compatibility (PKB) : -39.00 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.234

(partial model without unconserved sides chains): PDB file : Tito_5J9T.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5J9T-query.scw PDB file : Tito_Scwrl_5J9T.pdb: