Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLKIYGIKNCNSMKKAFDVLQAKGLSYEFHDYKKQGIDADTLKIWLKEIG--QDTVLNKKGTTWKKLSEEEQTRALSSEDHLIEALIAQPSLIKRPVLQTSKGFLVGFDETAYQNLSA 1Z3E Chain:A ((2-116)) MVTLYTSPSCTSCRKARAWLEEHEIPFVERNIFSEPLSIDEIKQILRMTEDGTDEIISTRSKVFQKLNVNVE-SM--PLQDLYRLINEHPGLLRRPIIIDEKRLQVGYNEDEIRRFLP

General information: TITO was launched using: RESULT: Template: 1Z3E.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 444 -6712 -15.12 -59.39 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : -15.12 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.685

(partial model without unconserved sides chains): PDB file : Tito_1Z3E.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Z3E-query.scw PDB file : Tito_Scwrl_1Z3E.pdb: