Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --MIVVTLTYKKPLTEV-DAVLKEHIAFLDHY--YEQKKFLASGRRENRVGGVILVLSSSIQEAEEIMKNDPFYIHDVADYDFMWFEPSKSLEEIKEFV 1WD6 Chain:A ((2-98)) ATLLQLHFAFNGPFGDAMAEQLKPLAESINQEPGFLWKVWTES-EKNHEAGGIYLFTDEKSALAYLEKHTARLKNLGVEEVVAKVFDVNEPLSQINQA-

General information: TITO was launched using: RESULT: Template: 1WD6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 328 -6198 -18.90 -67.37 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -18.90 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.172

(partial model without unconserved sides chains): PDB file : Tito_1WD6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1WD6-query.scw PDB file : Tito_Scwrl_1WD6.pdb: