TITO

Modeling by threading (Tito software)
Unconserved sides chains calculation (Scwrl software)
Evaluation (QMean software)

Input alignment information:

Query sequence

MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGLNQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMG----DYIEFLVIFAVLMLNSIISVVQTKKAEGSLEALKNLSAPDARVIRDGKE--KTIPANELVVGDIVLLDAGDYVPADGRLLDAGS--LKVDEGMLTGESTSAEKEVTDITSTVPIG-DRTNMVFSGTIVTYGRGKFLVTSTGNNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLS--LAILALSLLILGIQLFRIYLGEGTGDMTADIVSAVMF---AVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLGSTSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFT--------------------NDPSKWTADERRLIE---ISVLANDASISEDGTK-----LGDPTEVAFIDFSEKLNQPYQEIRNN----------------YPRQAELPFDSDRKLMSTGHTIDNK------NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFST--RALRVLAFAYRP---------LDNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIAKQIGIFEE----GNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHISAMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDNIKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEPATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLIWCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFGLTEVFTCMGIALVTIVLMEITKLIIVRVQGNK

4H1W Chain:A ((2-833))

-------EAAHSKSTEECLAYFGVSETTGLTPDQVKRHLEKYGHNELPAEEGKSLWELVIEQFEDLLVRILLLAACISFVLAWFETAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVSTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSW-----IRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGDFCSLNEFSITGSTYAPEGEVLKNDKPIRSGQFDGLVELATICALCNDSSLDFNETKGVYEKVGEATETALTTLVEKMNVFNTEVRNLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPMTGPVKEKILSVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSSRFMEYETDLTFVGVVGMLDPPRKEVMGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLIS------------------------------------------------------------------------------------------------------------------------------------

General information:

TITO was launched using:	RESULT:
Template: 4H1W.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output	Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 3803 41367 10.88 55.60 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : 10.88 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.473

(partial model without unconserved sides chains):
PDB file : Tito_4H1W.pdb:

(Unconserved sides chains are recalculated) :
Sequence: align-4H1W-query.scw
PDB file : Tito_Scwrl_4H1W.pdb: