Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTTPYKYQMLPMEKVFRDPVHNYIHVQHKVILDLINSKEVQRLRRIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLVTLCAALLHDVGHGPYSHTFEHIF--------HTNHEAITVEIITSP--ETEVYQILNRVEE---GFPEKVASVIQKTY-----------PNPQVVQMISS---QIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEG----GIAFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELHSQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATFSGNRDSKLVQ--E---LT-LLV-E------KVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG--TLIEL--SQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGALIEIN 4MZ7 Chain:B ((24-490)) --------HVDTMKVINDPIHGHIELH-PLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHALGEKQP-----ELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEEDIYFIKEQIVGPLESLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQ-NNFDYKRFIKFARVCEVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAFLKADDYIEITGA-----GGKKYRISTAIDDMEAYTKLTDNIFLEILYS-TDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAED-FIVDVINM-DYGM---QEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAE--QLIRVYCKKVDRK--------SLYAARQYFVQWCADRN-----

General information: TITO was launched using: RESULT: Template: 4MZ7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2032 -55305 -27.22 -133.59 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain B : 0.68 3D Compatibility (PKB) : -27.22 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.351

(partial model without unconserved sides chains): PDB file : Tito_4MZ7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4MZ7-query.scw PDB file : Tito_Scwrl_4MZ7.pdb: