Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -------------CVIGLTFNGNWVPNNRFVIS-PG----GKFSFIANYVIIPVRL-DESCH-WHQDLAE--------NAKP-----VIIPSGYGIKSCDEGDFVNNQCQEPPKR---TSIGGTKVYAFS----------- 1DT9 Chain:A ((143-296)) DSKFGFIVIDGSGALFGTLQGNTREVLHKFTVDLPKKHGRGGQS--ALRF---ARLRMEKRHNYVRKVAETAVQLFISGDKVNVAGLVLAGSADFKTELSQSDMFDQRLQSKVLKLVDISYGGE--NGFNQAIELSTEVLS

General information: TITO was launched using: RESULT: Template: 1DT9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 255 2860 11.22 32.87 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : 11.22 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.176

(partial model without unconserved sides chains): PDB file : Tito_1DT9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1DT9-query.scw PDB file : Tito_Scwrl_1DT9.pdb: