Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFTGCQNMSPSDQRIGAAAAGGALG-----GGLGNHVGGGIGAGLGAAVGAGVGSNTQGGSKQTTTKSAIGAGIGSVVGKAIIGSDTGAAIGGAIGGGAGAAIEEKK---- 2Q97 Chain:T ((1-109)) MQQELGLLRPEERLIAGQAKAAALQTVHQLGAVALTPEQAKAALLDEILRATQNLDLRKYENLNTEQQKAYEQVQRDLSQ--LSPETKALLIENQRKEKTLLEKARKLFQR

General information: TITO was launched using: RESULT: Template: 2Q97.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain T - contact count / total energy / energy per contact / energy per residue : 47 1376 29.28 13.76 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain T : 0.65 3D Compatibility (PKB) : 29.28 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.65 QMean score : -0.190

(partial model without unconserved sides chains): PDB file : Tito_2Q97.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Q97-query.scw PDB file : Tito_Scwrl_2Q97.pdb: