Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSTVPFVTCDLLDDNPEKDLQVVTPSMDGKSFKSYGARQTFGGQVVTVKCFEDNSRVKELLATDGTGKVLVVDGGASMRCALMGDMIAESAVKNNWNGVVIYGCVRDVDALATLDLGVHALAAIPQKSNRKGIGEVDIPLYFGGVTIQSGDFIYADNNGIVIAKEKLV 1Q5X Chain:A ((2-159)) ----KYDTSELCDIYQED-VNVVEP-----LFSNFGGRASFGGQIITVKCFEDNGLLYDLLEQNGRGRVLVVDGGGSVRRALVDAELARLAVQNEWEGLVIYGAVRQVDDLEELDIGIQAMAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLD

General information: TITO was launched using: RESULT: Template: 1Q5X.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 964 -125813 -130.51 -796.28 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.83 3D Compatibility (PKB) : -130.51 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.615

(partial model without unconserved sides chains): PDB file : Tito_1Q5X.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Q5X-query.scw PDB file : Tito_Scwrl_1Q5X.pdb: