Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQELANRLAIQNFVNAYMQETGKGYLLSFDQQSSTQQAFSSGSTLLTLPLPSIQAECSVPLSYVSRVGRHRLAALPKMC-IDGQWQKFSAGTIVSLLLEELVIESQFKLDAASLLEKWIQSRDALLQFLKQRHNDFDDLVKAGQNFIESEQALILGHSMHPAPKSRNGFVHEDWLKFSPEHAGKTQLHYWLVHQNYIAEGCAT---EQP-ISDQVKDAIRWCLSESDLNLLKTHVEFKLLPLHPWQARYLQGKPWFEQLKQTGQLIDIGLRGWQFSPTTPIRTLASFNA--PWMVKTSLSVMITNSIRVNLAKECHRGEISYRLWHSDLGKKILKQCPTLKAVNDPAWIALQID---------GEIINETICIFRDQPF---AVQQQVTCIASLCQDHPNKELNRFNALFDQIAQKNQQTNFKEIALDWFDHFLKIGLAPLMYVYHKYGMAFESHQQNVLLELEDGFPKNLWLRDNQGF-HYIEEFATEIVEALPDLLEKAHAVGPKDFVDE--RFSYYFFGNTLFGLINAIGATGYISEDELLIHLQQNLLQLLEQY--PDSTLLQGLLFNDSLPYKGNLLTRLHELDELIAPLEHQSVYVQLPNPLYVEQKDVSYA 2X0Q Chain:A ((18-603)) --PEIWNKVNRLLVRKAISEYAHEWLLEPQRLGP---GETPGFERFRLTLAD-GAQYDFDAQV-MAMRHWRIPPESIVKTVAGVPAPLDALQFVIEIRDKLGLP---VDRLPIYMDEITSTLHGSAYKHGRTTLGAA--ALARADYQTIETSMIEGHPSFVANNGRLGFDAEDYHGYAPEAATPVRLMWLAVHKDNAHFSCLSDMDYDSLMSEELGESAVTDFAARLREQGLHPADYYFMPAHPWQWFNKLSL-AFAPYVAQRKIVCLGYGEEQYLAQQSIRTFFNISRPGKRYVKTSLSILNMGFMRGLSPYYMAGTPAINEYIHDLISADPWLRANGFRILREVASMGFRNYYYEAAIDTDTPYKKMFSALWRENPLTLIAPGQNLMTMAALLHVDPQG-RALLPELIQAS-----G----LDAGTWLERYVDAYLTPLIHCFYAHDLVFMPHGENVILVIQDGVPVRAFMKDIAEESSILNPQV-----RLPQ--AAQRLAADVPEAYKLLTIFVDVFEGYFRHLTQILVETELMPEHDFWRLVAGRIAAYQQAHPQRLDKYRRYDLFAPDMIHSCLNRLQLAN--------------PNLPNPIACFRP-----

General information: TITO was launched using: RESULT: Template: 2X0Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2913 -81841 -28.09 -150.17 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -28.09 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.367

(partial model without unconserved sides chains): PDB file : Tito_2X0Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2X0Q-query.scw PDB file : Tito_Scwrl_2X0Q.pdb: