Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTKLAILILSLAFFGSAHADVKTLEQNLKTNYPDLPVKGVYQSPVAGIYEVYTSGRIVYTNQDAKYFFVGNLVDIKQQ--KNMTEERIAELGKIDVKSLPLNQAI-KYVKGKGERTLYIFSDPDCPYCQRLEQNMVGV--DNVTVYVFLYPLTSLHPNAEKVSNQIWCSKNPSEAWTNYMLNRKLPAAGKSCTSPVQKNIALGQKLNIDGTPTLFLQDGQKISGVPGDAKQIEELLQSVK 1T3B Chain:A ((3-209)) ----------------------AAIKRKLQS--FNISNIVIKSSPISGIKTAVTDQGILYVSEDGKYLFEGKLYELTNNGPVDVAGKILV----DKLNSYK-DEMIVYPA-KNEKHVVTVFMDITCHYCHLLHQQLKEYNDLGITVRYLAFPRAGMNNQTAKQMEAIWTAKDPVFALNEAEKGNL-P-KEVKTPNIVKKHYELGIQFGVRGTPSIVTSTGELIGGYLK-PADLLRALEET-

General information: TITO was launched using: RESULT: Template: 1T3B.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 925 6372 6.89 31.54 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : 6.89 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.504

(partial model without unconserved sides chains): PDB file : Tito_1T3B.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1T3B-query.scw PDB file : Tito_Scwrl_1T3B.pdb: