Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKMLIRKAKKDDTDTIVAIIAPYVDQVIAN-DEGRSRFKSEAIQTIFDREDIHYFVGEIDQQIVGIVAYME------------PSHLMHFFIKKTHLKLGLGRQLWDFIEEKIKNENIDIEKITVNSSFYAQDIYEKFGFIVSGDAAEKWGIRFIPMTKYYALASEK 3JVN Chain:A ((3-136)) --PVIRRAKEIDLYCLNSLMYKLHDEHHQQCPD------EKSIARYLDDPECMVYVAEMDDVIIGFITGHFCELISTVSKLVMMATIDELYIEKEYRREGVAEQLMMRIEQELKDYGVKEIFVEVW-NKGA------------------------------------

General information: TITO was launched using: RESULT: Template: 3JVN.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 385 -26868 -69.79 -246.50 target 2D structure prediction score : 0.47 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -69.79 2D Compatibility (Sec. Struct. Predict.) : 0.47 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.429

(partial model without unconserved sides chains): PDB file : Tito_3JVN.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3JVN-query.scw PDB file : Tito_Scwrl_3JVN.pdb: