Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --------MSANTFPAQIEPFKW-----------AEQGFTW-SGQLPLS-R-FARIAREAVGSIDNQLINIDCKLSMDAY---HRIVWLDGHMETKVPMECQRCLEPVE-MPIVSDFHIALVD-DESLIERLDEDADFIVLGE-SESSTKGDFDTPASINLLALLEDELLLLMPLSPKH-DACEHKHQPTIQNVVEEKRDN-PFDVLAGLKGKLNS 3BBD Chain:A ((2-205)) TYNIILAKSALELIPEEIKNKIRKSRVYKYDILDSNYHYKAMEKLKDKEMRGRPDIIHISLLNILDSPINHEKKLNIYIHTYDDKVLKINP--ETRLPRNYFRFLGV--MEKVLKGERNHLIKMEEKTLEDLLNEINAKKIAIMTKTGKL--------THPKLLKEYDTFIIGGFPYGKLKINKEKVFGDIKEISIYNKGLMAWTVCGIICYSLSF

General information: TITO was launched using: RESULT: Template: 3BBD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 787 41115 52.24 236.29 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : 52.24 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.194

(partial model without unconserved sides chains): PDB file : Tito_3BBD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3BBD-query.scw PDB file : Tito_Scwrl_3BBD.pdb: