Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEEL---AAQYPENYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE--------- 2LU2 Chain:A ((58-138)) EMTRLMVT-----EKQES--KNFSKMAKSQSFSTRIEELGGSISFLTETGVTMIELPKTVSEHDMDQLLHDILAAGGVVGLDSEVKLA

General information: TITO was launched using: RESULT: Template: 2LU2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 278 11044 39.72 162.40 target 2D structure prediction score : 0.47 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : 39.72 2D Compatibility (Sec. Struct. Predict.) : 0.47 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.275

(partial model without unconserved sides chains): PDB file : Tito_2LU2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2LU2-query.scw PDB file : Tito_Scwrl_2LU2.pdb: