Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVEQFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKVVKLPTLIQTISQKFKNLFAKK 5MV7 Chain:A ((433-503)) --------------------------LIAINRHGVLLIHPKTKDLLTTYPFTKISSWSSGS-T----Y-FHMAL--SRLLCETSLGYKMDDLLTSYVQQ------------------------

General information: TITO was launched using: RESULT: Template: 5MV7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 222 -51791 -233.29 -796.78 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : -233.29 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.586

(partial model without unconserved sides chains): PDB file : Tito_5MV7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5MV7-query.scw PDB file : Tito_Scwrl_5MV7.pdb: